Animal Health and Disease Research

The purpose of this funding is to increase animal health and disease research activities at accredited State veterinary schools or colleges or agricultural experiment stations that conduct animal health and disease research.

To support animal health and disease research at eligible Schools and

credit: Photo by Jim McCormac
Colleges of Veterinary Medicine, and State Agricultural Experiment Stations whose purpose is to improve the health and productivity of food animals and horses through effective prevention, control or treatment of disease, reduction of losses from transportation and other hazards, and protect human health through control of animal diseases transmissible to people.
Related Programs

Examples of Funded Projects

Fiscal Year 2016: Forty percent (48%) of the awards were less than $30,000 each.

Because so many smaller studies are supported annually, some aspect of each of the topic areas listed below are generally represented in one (1) or more projects each program year.

In accordance with the legal authority for this program, all of the following project topic areas relate directly toward the enhancement of animal health through the support of research activities related to: (1) reducing the incidence of food-borne illness and to provide a safer food supply; and (2) to protect animal health by minimizing disease transmission through improved basic and applied mechanisms to prevent and control disease in livestock (i.e., vaccinology, improved diagnostic testing and capabilities, and improved herd and flock management).

Fiscal Year 2017: Forty-two percent (42%) of the institutional awards were less than $30,000 each.

Because so many smaller studies will be supported annually, some aspect of each of the topic areas listed below are generally represented in one (1) or more projects each program year.

In accordance with the legal authority for this program, all of the following project topic areas relate directly toward the enhancement of animal health through the support of research activities related to: (1) reducing the incidence of food-borne illness and to provide a safer food supply; and Fiscal Year (FY) 2017: Forty-two percent (42%) of the institutional awards were less than $30,000 each.

Because so many smaller studies will be supported annually, some aspect of each of the topic areas listed below are generally represented in one (1) or more projects each program year.

In accordance with the legal authority for this program, all of the following project topic areas relate directly toward the enhancement of animal health through the support of research activities related to: (1) reducing the incidence of food-borne illness and to provide a safer food supply; and (2) to protect animal health by minimizing disease transmission through improved basic and applied mechanisms to prevent and control disease in livestock (i.e., vaccinology, improved diagnostic testing and capabilities, and improved herd and flock management). Example of funded Research in Swine ? NOVEL PORCINE EPIDEMIC DIARRHEA VIRUS VACCINE PIPELINE Recent emergence of extremely contagious Porcine Epidemic Diarrhea virus (PEDV) with 80-100% mortality in neonate pigs calls for the development of an effective prophylactic vaccine.

PED has been such an important disease that it brought attention to the NIFA Animal Health and Disease priority area (A1221).

In this seed grant proposal, we propose to develop an effective novel vaccine candidate against PEDV infection.

We will produce a ferritin nanoparticle immunogen coated with PEDV's spike (S) glycoprotein to induce neutralizing antibodies.

We will formulate this novel nanoparticle into a Newcastle virus (NDV) vector with mucosal tropism derived from an attenuated vaccine strain LaSota.

The NDV vector is effective in inducing protective immunity at both the mucosal and systemic levels and it has been extensively used to express various antigens of important viral diseases including the full-length spike glycoprotein of SARS coronavirus.

Resultant vector vaccines have shown safe and protective efficacies in different animal models, and NDV vector replication in eggs is amenable to large scale and rapid production.

We hypothesize that the nanoparticle vaccine delivered by NDV vector mimic native viruses, which in turn elicit high titer neutralizing antibody responses and provide protection against PEDV infection in pigs.

We propose to employ a pregnant sow model to test this hypothesis.

Sow model is of clinical relevance because successful vaccination of sows is likely to play an important role in the control and eradication of PED epidemics in piglets. Example of funded research in Feeder Cattle ? ALTERING THE TIME OF VACCINATION AGAINST RESPIRATORY PATHOGENS TO ENHANCE VACCINE EFFICACY, HEALTH, AND PERFORMANCE OF FEEDER CATTLE The focus of this research project is to compare the effects of anticipated (15 days prior), delayed (15 days after), or vaccination at the time of weaning and feedlot entry on vaccine efficacy, health, and performance variables of feeder cattle. Example of funded research in Dairy Cattle ? ENHANCING DISEASE RESISTANCE IN DAIRY CATTLE The long term goal of this project is to reduce the use of antimicrobials in dairy cattle by providing new methods to optimize innate immunity through nutritional and/or targeted pharmacological approaches during time of increased susceptibility to disease.

Many dairy cattle diseases during the early lactation period can result from dysfunctional inflammatory responses that are characterized by an imbalance of the robust initial response needed for pathogen clearance and the prompt return to immune homeostasis.

The initiation and resolution of the inflammatory response is regulated by the production of potent lipid mediators.

The potential benefits of reducing inflammatory-based diseases of early lactation dairy cattle through modification of lipid metabolism has not been explored in depth.

Therefore, the immediate goals of this project are to not only identify how lipid mediator biosynthesis changes during the transition period and during disease, but also the potential impact that lipid metabolism has on macrophage inflammatory functions.

Therefore, the objectives of this project are to: (1) describe changes in lipid mediator biosynthesis during the transition period; (2) describe changes in lipid mediator biosynthesis during mastitis; and (3) determine the underlying mechanisms of how lipid mediators can impact macrophage inflammatory functions. Example of funded research in Poultry ? SAFE AND COST-EFFECTIVE NEXT GENERATION VACCINES AGAINST INFECTIOUS VIRUSES USING ESTABLISHED IMMORTAL AVIAN CELL LINES The goal of this proposal is to improve animal health by developing an optimal system for the production of infectious vaccine viruses of genetically engineered-, non-reversible and live attenuated vaccines using established immortal avian cell lines.

The specific objectives are to: (1) attenuate virulent and vaccine virus strains using immortal avian cell lines; (2) develop a new reverse genetics system retaining the complete full length sequence of viral RNA genome of vaccine strain using a novel artificial bacterial chromosome (BAC) vector and immortal avian cell line substrates to produce vaccine candidates; (3) compare commercial vaccines with the newly generated vaccines in this project in terms of immunogenic activity and protective efficacy; and (4) produce a large quantity of optimally infectious vaccine strains for the use of vaccination in commercial setting. Example of funded research in sheep ? ENDOCRINE DISRUPTING CHEMICALS AND PREGNANCY HEALTH IN SHEEP The overall objective of this proposal is to define the molecular mechanisms whereby bisphenolic compounds (BPA, and BPA replacement chemicals) with estrogenic potential can induce placental dysfunction during pregnancy.

Studies described in this proposal will test a novel hypothesis to assess the disease risk of exposure to endocrine disrupting chemicals during pregnancy in a relevant agricultural species, such as the sheep.

Objectives: (1) to test if gestational exposure to BPA or BPA replacement compounds leads to a disruption in the maternal endocrine milieu and fetal growth in sheep; (2) to test if gestational exposure to BPA or BPA replacement compounds leads to a disruption in placental function; and (3) to test if exposure to BPA or BPA replacement compounds impairs placental steroidogenic potential.

Fiscal Year 2018: This program is subject to congressional budget approval for FY 2018.

At this time, the projected funding level is Zero ($0).

However, if funding is provided, it is anticipated that numerous smaller (less than $30,000 each) institutes receiving less than $30,000 will make-up about 40% of the future funded projects.

Because so many smaller studies will be supported annually, some aspect of each of the topic areas listed below will generally be represented in one (1) or more projects each program year.

In accordance with the legal authority for this program, all of the following project topic areas relate directly toward the enhancement of animal health through the support of research activities related to: (1) reducing the incidence of food-borne illness and to provide a safer food supply; and (2) to protect animal health by minimizing disease transmission through improved basic and applied mechanisms to prevent and control disease in livestock (i.e., vaccinology, improved diagnostic testing and capabilities, and improved herd and flock management).


Agency - Department of Agriculture

Established in 1862, the Department of Agriculture serves all Americans through anti-hunger efforts, stewardship of nearly 200 million acres of national forest and rangelands, and through product safety and conservation efforts. The USDA opens markets for American farmers and ranchers and provides food for needy people around the world.


Relevant Nonprofit Program Categories





Selected Recipients for this Program


RecipientAmount Start DateEnd Date
Iowa State University Of Science And Technology $ 108,840   2015-10-012017-09-30
Iowa State University Of Science And Technology $ 100,035   2015-10-012017-09-30
Washington State University $ 113,514   2015-10-012017-09-30
Board Of Regents Of The University Of Nebraska $ 111,909   2015-10-012017-09-30
Cornell University, Inc $ 104,494   2015-10-012017-09-30
Regents Of The University Of California, The $ 261,749   2015-10-012017-09-30
Texas A&m Agrilife Research $ 286,765   2015-10-012017-09-30
Kansas State University $ 140,091   2015-10-012017-09-30
Colorado State University $ 309,011   2015-10-012017-09-30
Regents Of The University Of Minnesota $ 90,760   2015-10-012017-09-30



Program Accomplishments

Fiscal Year 2016: Sixty-seven Capacity block grants, for a total of $3,706,320, as determined by the legislatively mandated formula and computed by the Office of Grants and Financial Management (OGFM), were awarded to 67 eligible State entities (all Agricultural Experiment Stations and U.S. Veterinary Colleges). These funds were used at the discretion of authorized Deans and Directors to address local, regional or national agricultural animal health and disease research priorities of their respective states. Fiscal Year 2017: Sixty-seven Capacity block grants, for a total of $3,696,260, as determined by the legislatively mandated formula and computed by the Office of Grants and Financial Management (OGFM), will be awarded to 67 eligible State entities (all Agricultural Experiment Stations and US Veterinary Colleges). These funds were used at the discretion of authorized Deans and Directors to address local, regional or national agricultural animal health and disease research priorities of their respective states. Participation by Lincoln Memorial University (new Veterinary School in Tennessee) commenced in Fiscal Year 2017. The Alaska State Agricultural Experiment Stations (SAES) chose not to participate. Fiscal Year 2018: This program is subject to congressional budget approval for FY 2018. At this time, the projected funding level is Zero ($0). However, if funded in FY 2018: NIFA anticipates Sixty-eight Capacity block grants, for a projected amount similar to FY 2017. The projected total, as determined by the legislatively mandated formula and computed by the Office of Grants and Financial Management (OGFM), will be awarded to 68 eligible State entities (all Agricultural Experiment Stations and US Veterinary Colleges). These funds will be used at the discretion of authorized Deans and Directors to address local, regional or national agricultural animal health and disease research priorities of their respective states. Midwestern University (new Veterinary School in Arizona) is scheduled to participate in FY 2018.

Uses and Use Restrictions

The National Institute of Food and Agriculture (NIFA) requests applications for the FY 2009 formula grants authorized under authorized under section 1433 of the National Agricultural Research, Extension, and Teaching Policy Act of 1977 (NARETPA) for the Animal Health and Disease Research (AHDR) Program.

These grants are used to assist all states in carrying out a program of research activities designed to: (1) to meet expenses of conducting animal health and disease research, publishing and disseminating the results of such research, and contributing to the retirement of employees subject to the provisions of the Act of March 4, 1940 (54 Stat.

39?40, as amended; 7 U.S.C.

331); (2) for administrative planning and direction; and (3) to purchase equipment and supplies necessary for conducting such research.

States are eligible for funds appropriated under this Act according to the following formula: One half of the State allotment will be distributed among the States in the proportion that the value of and income to producers from domestic livestock, poultry, and commercial aquaculture species in each State bears to the total value of and income to producers from domestic livestock, poultry, and commercial aquaculture species in all the States, based on the most current inventory of all cattle, sheep, swine, horses, poultry, and commercial aquaculture species published by the U. S. Department of Agriculture.

The remainder of the State allotment will be distributed among the States in the proportion that the animal health and disease research capacity of the eligible institutions in each State bears to the total animal health and disease research capacity in all the States, as determined by NIFA. Uses: Research on animal health and disease of food animals and horses conducted in eligible institutions under the following categories: (1) Infectious diseases; (2) internal and external parasites; (3) noninfectious diseases, toxins, poisons, transportation losses, predators and other hazards; (4) diseases and parasites of wildlife transmissible to food animals and horses; and (5) diseases and parasites of animals transmissible to people.

Restrictions: (1) Approved NIFA AHDR Projects AHDR Federal funding must be used on AHDR approved projects.

(2) Matching 7 U.S.C.

3200 provides that ?No funds in excess of $100,000 ? shall be paid by the Federal Government to any State under this subchapter during any fiscal year in excess of the amount from non-Federal sources made available to and budgeted for expenditure by eligible institutions in the State during the same fiscal year for animal health and disease research.

The Secretary is authorized to make such payments in excess of $100,000 on the certificate of the appropriate official of the eligible institution having charge of the animal health and disease research for which such payments are to be made.

If any eligible institution certified for receipt of matching funds fails to make available and budget for expenditure for animal health and disease research in any fiscal year sums at least equal to the amount for which it is certified, the difference between the Federal matching funds available and the funds made available to and budgeted for expenditure by the eligible institution shall be reapportioned by the Secretary among other eligible institutions of the same State, if there are any which qualify therefor, and, if there are none, the Secretary shall reapportion such difference among the other States.? (3) Indirect Costs and Tuition Remission In accordance with section 1473 of the National Agricultural Research, Extension, and Teaching Policy Act of 1977 (7 U.S.C.

3319), indirect costs and tuition remission are unallowable as AHDR formula grant expenditures.

Fully discretionary.

Eligibility Requirements

Applicant Eligibility

Eligibility is restricted to the following public nonprofit institutions having demonstrable capacity in animal disease research: (1) Schools and Colleges of Veterinary Medicine; and (2) State Agricultural Experiment Stations.

Funds are appropriated by Congress for distribution to States and eligible State institutions according to the statutory formula stated in the Act. Applications may be submitted by accredited State veterinary schools or colleges or agricultural experiment stations that conduct animal health and disease research in accordance with NARETPA section 1433(c): Auburn University, Agricultural Experiment Station; Auburn University, School of Veterinary Medicine; Tuskegee University, School of Veterinary Medicine; University of Alaska, Agricultural Experiment Station; University of Arizona, Agricultural Experiment Station; University of Arkansas, Agricultural Experiment Station; University of California-Oakland, Agricultural Experiment Station; University of California-Davis, School of Veterinary Medicine; Colorado State University, Agricultural Experiment Station and College of Veterinary Medicine; University of Connecticut-Storrs, Agricultural Experiment Station; University of Delaware, Agricultural Experiment Station; University of Florida, Agricultural Experiment Station; University of Florida, College of Veterinary Medicine; University of Georgia, Agricultural Experiment Station; University of Georgia, College of Veterinary Medicine; University of Hawaii, Agricultural Experiment Station; University of Idaho, Agricultural Experiment Station; University of Illinois, Agricultural Experiment Station and College of Veterinary Medicine; Purdue University, Agricultural Experiment Station and College of Veterinary Medicine; Iowa State University, Agricultural and Home Economics Experiment Station; Iowa State University, College of Veterinary Medicine; Kansas State University, Agricultural Experiment Station and College of Veterinary Medicine; University of Kentucky, Agricultural Experiment Station; Louisiana State University, Agricultural Experiment Station; Louisiana State University, College of Veterinary Medicine; University of Maine, Agricultural Experiment Station; University of Maryland, Agricultural Experiment Station; University of Massachusetts, Agricultural Experiment Station; Tufts University, School of Veterinary Medicine; Michigan State University, Agricultural Experiment Station and College of Veterinary Medicine; University of Minnesota, Agricultural Experiment Station; University of Minnesota, College of Veterinary Medicine; Mississippi State University, Agricultural and Forestry Experiment Station and College of Veterinary Medicine; University of Missouri, Agricultural Experiment Station; University of Missouri, College of Veterinary Medicine; Montana State University, Agricultural Experiment Station; University of Nebraska, Agricultural Experiment Station; University of Nevada, Agricultural Experiment Station; University of New Hampshire, Agricultural Experiment Station; Rutgers University, Agricultural Experiment Station; New Mexico State University, Agricultural Experiment Station; Cornell University, Agricultural Experiment Station; Cornell University, College of Veterinary Medicine; North Carolina State University, Agricultural Experiment Station; North Carolina State University, College of Veterinary Medicine; North Dakota State University, Agricultural Experiment Station; Ohio State University, Ohio Agricultural Research & Development Center; Ohio State University, College of Veterinary Medicine; Oklahoma State University, Agricultural Experiment Station and College of Veterinary Medicine; Oregon State University, Agricultural Experiment Station; Pennsylvania State University, Agricultural Experiment Station; University of Pennsylvania, College of Veterinary Medicine; University of Puerto Rico, Agricultural Experiment Station; University of Rhode Island, Agricultural Experiment Station; Clemson University, Agricultural Experiment Station; South Dakota State University, Agricultural Experiment Station; University of Tennessee, Agricultural Experiment Station; University of Tennessee, College of Veterinary Medicine; Texas A&M University, Agricultural Experiment Station and College of Veterinary Medicine; Utah State University, Agricultural Experiment Station; University of Vermont, Agricultural Experiment Station; Virginia Polytechnic Institute and State University, Agricultural Experiment Station and College of Veterinary Medicine; Washington State University, Agricultural Experiment Station and College of Veterinary Medicine; West Virginia University, Agricultural and Forestry Experiment Station; University of Wisconsin, Agricultural Experiment Station and College of Veterinary Medicine; and University of Wyoming, Agricultural Experiment Station.

Award recipients may subcontract to organizations not eligible to apply for funding provided that such arrangements are necessary to complete the project or activity.

Beneficiary Eligibility

Eligibility is restricted to the following public nonprofit institutions having demonstrable capacity in animal disease research: (1) Schools and Colleges of Veterinary Medicine; and (2) State Agricultural Experiment Stations. Funds are appropriated by Congress for distribution to States and eligible State institutions according to the statutory formula stated in the Act.

Credentials/Documentation

The System for Award Management (SAM) combines eight federal procurement systems, including CCR, and the Catalog of Federal Domestic Assistance into one new system. CCR activities are conducted through SAM (the CCR website will redirect users to SAM). Dun and Bradstreet Universal Numbering System (DUNS) Number and System for Award Management (SAM): Each applicant (unless excepted under 2 CFR § 25.110(b) or (c), or has an exception approved by the Federal awarding agency under 2 CFR § 25.110(d)) is required to: (i) Be registered in SAM before submitting its application; (ii) Provide a valid DUNS number in its application; and (iii) Continue to maintain an active SAM registration with current information at all times during which it has an active Federal award or an application or plan under consideration by a Federal awarding agency. It also must state that the Federal awarding agency may not make a Federal award to an applicant until the applicant has complied with all applicable DUNS and SAM requirements and, if an applicant has not fully complied with the requirements by the time the Federal awarding agency is ready to make a Federal award, the Federal awarding agency may determine that the applicant is not qualified to receive a Federal award and use that determination as a basis for making a Federal award to another applicant. Applicants must furnish the information required in the Request for Applications (RFAs). Successful applicants recommended for funding must furnish the information and assurances requested during the award documentation process. These include, but are not limited to the following: Organizational Management Information - Specific management information relating to an applicant shall be submitted on a one time basis, with updates on an as needed basis, as part of the responsibility determination prior to the award of a grant identified under this RFA, if such information has not been provided previously under this or another NIFA program. NIFA will provide copies of forms recommended for use in fulfilling these requirements as part of the preaward process. Although an applicant may be eligible based on its status as one of these entities, there are factors which may exclude an applicant from receiving Federal financial and nonfinancial assistance and benefits under this program (e.g., debarment or suspension of an individual involved or a determination that an applicant is not responsible based on submitted organizational management information). This information collection is approved under OMB Circular Control No. 0524-0026, ?Assurance of Compliance with the Department of Agriculture Regulations Assuring Civil Rights, Compliance and Organization Information.? SPECIAL NOTE: Please refer to the Capacity, Competitive, and/or Non-Competitive Request for Applications (RFAs) for further specific and pertinent details. The most current RFAs are available as follows: https://nifa.usda.gov/program/animal-health-and-disease-research-program RFAs are generally released annually. Hence, the RFAs provide the most current and accurate information available. Any specific instructions in the Capacity, Competitive, and/or Non-Competitive RFAs supersede the general information provided in the CFDA database. 2 CFR 200, Subpart E - Cost Principles applies to this program.

Aplication and Award Process

Preapplication Coordination

All Request for Applications (RFAs) are published on the Agency?s website and Grants.gov.

Applicants must complete the Grants.gov registration process.

Application packages complement, rather than duplicate, the information collected via the Plan of Work (POW) system and the Research, Extension, and Education Project Online Reporting Tool (REEport), and together satisfy all legislative and regulatory pre-award requirements.

Please see the following NIFA Agency link for more information: http://nifa.usda.gov/program/animal-health-research-and-disease-program.

An environmental impact statement is required for this program.

This program is excluded from coverage under E.O.

12372.

Application Procedures

2 CFR 200, Uniform Administrative Requirements, Cost Principles, and Audit Requirements for Federal Awards applies to this program. Applications should be submitted as outlined in the RFA. Applicants must follow the instructions provided per Grants.gov. Application packages complement, rather than duplicate, the information collected via the Plan of Work (POW) system and the Research, Extension, and Education Project Online Reporting Tool (REEport), and together satisfy all legislative and regulatory pre-award requirements. The National Institute of Food and Agriculture (NIFA) only accepts electronic applications which are submitted via Grants.gov in response to specific Requests for Applications (RFA). Applicants must complete the Grants.gov registration process. For information about the pre-award phase of the grant lifecycle application processes see: http://www.grants.gov/web/grants/learn-grants/grants-101/pre-award-phase.html. Further, applicants must follow the instructions provided in the NIFA Grants.gov Application Guide, which can be assessed as follows: Adobe NIFA Applications. 2 CFR part 200, Uniform Administrative Requirements, Cost Principles, and Audit Requirements for Federal Awards and 2 CFR part 400 USDA?s Uniform Administrative Requirements, Cost Principles, and Audit Requirements for Federal Awards apply to this program. SPECIAL NOTE: Please refer to the Capacity, Competitive, and/or Non-Competitive Request for Applications (RFAs) for further specific and pertinent details. The most current RFAs are available via: https://nifa.usda.gov/program/animal-health-and-disease-research-program RFAs are generally released annually. Hence, the RFAs provide the most current and accurate information available. Any specific instructions in the Capacity, Competitive, and/or Non-Competitive RFAs supersede the general information provided in the CFDA database.

Award Procedures

Funds will be released on a quarterly basis to the institutions. See Appendix A of the Request for Application (RFA) for the specific allocation. AHDR funds must be fully expended in the fiscal year of appropriation; no waiver requests may be considered and approved as no carryover authority is provided in the authorizing legislation. 2 CFR Part 200 ? Subpart C and Appendix I apply to this program. 2 CFR Part 400 applies to this program. Applications are subjected to a system of peer and merit review in accordance with section 103 of the Agricultural Research, Extension and Education Reform Act of 1998 (7 U.S.C. 7613) by a panel of qualified scientists and other appropriate persons who are specialists in the field covered by the proposal. Within the limit of funds available for such purpose, the NIFA Authorized Departmental Officer (ADO) shall make grants to those responsible, eligible applicants whose applications are judged most meritorious under the procedures set forth in the RFA. Reviewers will be selected based upon training and experience in relevant scientific, extension, or education fields, taking into account the following factors: (a) The level of relevant formal scientific, technical education, or extension experience of the individual, as well as the extent to which an individual is engaged in relevant research, education, or extension activities; (b) the need to include as reviewers experts from various areas of specialization within relevant scientific, education, or extension fields; (c) the need to include as reviewers other experts (e.g., producers, range or forest managers/operators, and consumers) who can assess relevance of the applications to targeted audiences and to program needs; (d) the need to include as reviewers experts from a variety of organizational types (e.g., colleges, universities, industry, state and Federal agencies, private profit and non-profit organizations) and geographic locations; (e) the need to maintain a balanced composition of reviewers with regard to minority and female representation and an equitable age distribution; and (f) the need to include reviewers who can judge the effective usefulness to producers and the general public of each application. Evaluation Criteria will be delineated in the Capacity, Competitive, and/or Non-Competitive Request for Applications (RFA). 2 CFR 200 ? Subpart C and Appendix I and 2 CFR part 400 apply to this Program. SPECIAL NOTE: Please refer to the Capacity, Competitive, and/or Non-Competitive Request for Applications (RFAs) for further specific and pertinent details. The most current RFAs are available via: https://nifa.usda.gov/program/animal-health-and-disease-research-program RFAs are generally released annually. Hence, the RFAs provide the most current and accurate information available. Any specific instructions in the Capacity, Competitive, and/or Non-Competitive RFAs supersede the general information provided in the CFDA database.

Deadlines

Contact the headquarters or regional office, as appropriate, for application deadlines.

Authorization

Executive Order National Agricultural Research, Extension, and Teaching Policy Act of 1977, Section 1433, Public Law 95-113, as amended; Section 1429, Public Law 97-98; Public Law 99-198; Public Law 101-624; Public Law 104-127; Public Law 105-185. , 7 U.S.C 3195.

Range of Approval/Disapproval Time

From 30 to 60 days. From 30 to 60 days. Contact the National Program Leader (NPL), as indicated per CFDA Section # 152 ? Headquarters Office regarding dates for specific deadlines, start and end dates, and range of approval/disapproval time. Information is also available via our website and may be obtained via the Grants.gov website. NIFA?s respective links regarding general information are provided below: http://nifa.usda.gov/ http://www.grants.gov. SPECIAL NOTE: Please refer to the Capacity, Competitive, and/or Non-Competitive Request for Applications (RFAs) for further specific and pertinent details. The most current RFA is available via: https://nifa.usda.gov/program/animal-health-and-disease-research-program RFAs are generally released annually. Hence, the RFAs provide the most current and accurate information available. Any specific instructions in the Capacity, Competitive, and/or Non-Competitive RFAs supersede the general information provided in the CFDA database.

Appeals

Not Applicable. 2 CFR Part 200 ? Subparts D & E apply to this program.

Renewals

Specific details are provided in the Request for Applications (RFA), which are generally published annually. The most current RFA is available via: https://nifa.usda.gov/program/animal-health-and-disease-research-program.

Assistance Considerations

Formula and Matching Requirements

Statutory Formula: Title Food and Agriculture Act of 1977, Public Law 95-113. Public Law 95-113, As Amended Through P.L. 113-79, Enacted February 7, 2014. Matching Requirements: 7 U.S.C. 3200 provides that ?No funds in excess of $100,000 ? shall be paid by the Federal Government to any State under this subchapter during any fiscal year in excess of the amount from non-Federal sources made available to and budgeted for expenditure by eligible institutions in the State during the same fiscal year for animal health and disease research. The Secretary is authorized to make such payments in excess of $100,000 on the certificate of the appropriate official of the eligible institution having charge of the animal health and disease research for which such payments are to be made. If any eligible institution certified for receipt of matching funds fails to make available and budget for expenditure for animal health and disease research in any fiscal year sums at least equal to the amount for which it is certified, the difference between the Federal matching funds available and the funds made available to and budgeted for expenditure by the eligible institution shall be reapportioned by the Secretary among other eligible institutions of the same State, if there are any which qualify therefore, and, if there are none, the Secretary shall reapportion such difference among the other States.?. MOE requirements are not applicable to this program.

Length and Time Phasing of Assistance

AHDR funds must be fully expended in the fiscal year of appropriation; no waiver requests may be considered and approved as no carryover authority is provided in the authorizing legislation. 2 CFR Part 200, Subpart D applies to this program. AHDR funds are expected to be fully expended in the fiscal year of appropriation; however, funds may be carried over for up to one (1) additional year. Please note that there is no limitation on the amount of federal funds that may be carried over for this one (1) additional fiscal year. No prior approval from NIFA is required. Since this limitation is legislatively mandated, NIFA is not authorized to grant any carry-over requests beyond this one (1) additional year. Further details are provided in the Award document Form NIFA-2009 and the NIFA General Terms and Conditions Grants and Cooperative Agreements (dated October 2016) at: https://nifa.usda.gov/resource/nifa-general-terms-and-conditions-grants-and-cooperative-agreements-october-2016. SPECIAL NOTE: Please refer to the Capacity, Competitive, and/or Non-Competitive Request for Applications (RFAs) for specific and pertinent details. The most current RFAs are available via: https://nifa.usda.gov/program/animal-health-and-disease-research-program RFAs are generally released annually. Hence, the RFAs provide the most current and accurate information available. Any specific instructions in the Capacity, Competitive, and/or Non-Competitive RFAs supersede the general information provided in the CFDA database. See the following for information on how assistance is awarded/released: NIFA utilizes the Automated Standard Application for Payments (ASAP), a secure, web-based electronic payment and information system that allows federal agencies to administer funds. Currently, ASAP is the only payment source for new NIFA grantees.

Post Assistance Requirements

Reports

Grantees are to submit initial project information and annual summary reports to NIFA?s electronic, Web-based inventory system that facilitates both grantee submissions of project outcomes and public access to information on Federally-funded projects.

The details of the reporting requirements are included in the award terms and conditions. Application packages complement, rather than duplicate, the information collected via the Plan of Work (POW) system and the Research, Extension, and Education Project Online Reporting Tool (REEport), and together satisfy all legislative and regulatory pre-award requirements.

Institutions are expected to submit an annual Program of Research, which is a listing of all approved AHDR projects for said institution.

Institutions must submit a Project Initiation form through the REEport System prior to the initiation of each AHDR project.

The project must undergo a review process and be approved before it is incorporated into the Program of Research.

Each institution shall submit a REEport Progress Report, annually for each eligible project.

These reports shall be submitted by February 1 for the preceding fiscal year. A Final Report shall be submitted through REEport to NIFA for each completed or terminated project.

Such reports shall be submitted at the same time as are Progress Reports on active projects and should include a brief summary of accomplishments for the entire life of the project.

A REEport Project Financial Report, shall be submitted to NIFA annually for all projects.

Reports shall be made on a fiscal year basis and are to be submitted by February 1. Financial reporting via the SF-425, Federal Financial Report are due annually to the Capacity Grants Branch, Awards Management Division, OGFM, on December 31st, for the period of October 1st through September 30th, on an annual basis until the award is closed out. For additional details regarding the annual, final technical and financial reporting requirements, please refer to the Agency?s website titled ?Animal Health Research and Disease Program? at: http://nifa.usda.gov/program/animal-health-research-and-disease-program Instructions for using the REEport system are included on the NIFA web site at: http://nifa.usda.gov/reeport-resources-land-grant-partners. Capacity Grants Branch Awards Management Division (AMD) Office of Grants and Financial Management (OGFM) National Institute of Food and Agriculture (NIFA) U.S.

Department of Agriculture (USDA) STOP 2271 1400 Independence Avenue, SW Washington, DC 20250-2298 Telephone: (202) 401-6520 Fax: (202) 690-3002 E-mail: formulagrantquestions@nifa.usda.gov.

NIFA uses the SF-425, Federal Financial Report to monitor cash.

(Pertinent details regarding Progress Reports are provided above.).

(Pertinent details regarding Expenditure Reports are provided above.).

(Pertinent details regarding Performance Monitoring Reports are provided above.).

Audits

In accordance with the provisions of 2 CFR 200, Subpart F - Audit Requirements, non-Federal entities that expend financial assistance of $750,000 or more in Federal awards will have a single or a program-specific audit conducted for that year. Non-Federal entities that expend less than $750,000 a year in Federal awards are exempt from Federal audit requirements for that year, except as noted in 2 CFR 200.503. In accordance with 2 CFR Part 400 - Uniform Administrative Requirements, Cost Principles, and Audit Requirements for Federal Awards, Subpart F - Audit Requirements nonfederal entities that expend financial assistance of $750,000 or more during the non-Federal entity's fiscal year in Federal awards must have a single or program-specific audit conducted for that year in accordance with the provisions of this part. A non-Federal entity that expends less than $750,000 during the non-Federal entity's fiscal year in Federal awards is exempt from Federal audit requirements for that year, except as noted in § 200.503. Relation to other audit requirements, but records must be available for review or audit by appropriate officials of the Federal agency, pass-through entity, and Government Accountability Office (GAO). This program is also subject to audit by the cognizant Federal audit agency and the USDA Office of Inspector General. Relation to other audit requirements, but records must be available for review or audit by appropriate officials of the Federal agency, pass-through entity, and Government Accountability Office (GAO). This program is also subject to audit by the cognizant Federal audit agency and the USDA Office of Inspector General.

Records

In accordance with 2 CFR Part 400 - Uniform Administrative Requirements, Cost Principles, and Audit Requirements for Federal Awards, § 200.333 Retention requirements for records. Grantees shall maintain separate records for each grant to ensure that funds are used for authorized purposes. Grant-related records are subject to inspection during the life of the grant and must be retained at least three (3) years. Records must be retained beyond the three (3) year period if litigation is pending or audit findings have not been resolved. 2 CFR Part 200, Subpart D applies to this program.

Financial Information

Account Identification

12-1500-0-1-352.

Obigations

(Formula Grants (Apportionments)) FY 16 $3,706,320; FY 17 est $3,696,260; and FY 18 est $0 - The difference between the appropriation and obligation numbers reflects legislative authorized set-asides deducted as appropriate, and in some cases the availability of obligational authority from prior years. NOTE: For FY 2018, a Budget was not requested to fund this program.

Range and Average of Financial Assistance

If minimum or maximum amounts of funding per Capacity, Competitive, and/or Non-Competitive project grant, or cooperative agreement are established, these amounts will be announced in the annual Capacity, Competitive, and/or Non-Competitive Request for Application (RFA). The most current RFA is available via: https://nifa.usda.gov/program/animal-health-and-disease-research-program.

Regulations, Guidelines, and Literature

As an administrator of U.S. government support, NIFA works in partnership with grantees to ensure responsible stewardship of federal funds. Our grantees and partners are required to comply with all relevant rules and regulations. The following resources are provided to NIFA?s partners and award recipients to support their adherence to federal regulations governing program performance: NIFA?s primary (main) website: https://nifa.usda.gov/regulations-and-guidelines The following represent specific documents and direct links: POLICY GUIDE NIFA?s Federal Assistance Policy Guide describes agency policies and procedures. https://nifa.usda.gov/policy-guide CERTIFICATIONS AND REPRESENTATIONS Certifications and representations provided through the NIFA application process. https://nifa.usda.gov/certifications-and-representations ACKNOWLEDGEMENT OF USDA SUPPORT BY NIFA When acknowledging USDA support in accordance with 2 CFR Part 415, grantees must use the following acknowledgement for all projects or initiatives supported by NIFA. https://nifa.usda.gov/acknowledgment-usda-support-nifa FEDERAL REGULATIONS The Code of Federal Regulations (CFR) lists all regulations published in the Federal Register. https://nifa.usda.gov/federal-regulations FOIA The Freedom of Information Act (FOIA) provides that any person has the right to request access to federal documents and information such as research data. https://nifa.usda.gov/foia NEPA POLICY AND GUIDANCE The National Environmental Policy Act (NEPA) Policy and Guidance set the standard for identifying potential environmental impacts. https://nifa.usda.gov/nepa-policy-and-guidance OGFM ISSUED CORRESPONDENCE The Office of Grants and Financial Management occasionally issues correspondence to applicants, grantees, and/or the general public for informational or clarification purposes. https://nifa.usda.gov/ogfm-issued-correspondence RESEARCH MISCONDUCT NIFA requires that all its awardees adhere to the USDA Scientific Integrity Policy and the Federal Policy on Research Misconduct. https://nifa.usda.gov/research-misconduct NIFA?S GENERAL AWARD TERMS AND CONDITIONS Award terms and conditions are determined by statutory, regulatory, and agency requirements, as well as each grant?s circumstances. Terms and conditions dictate important items related to your grant, including method of payment, reporting frequency and content, and prior approval requirements. References to the terms and conditions of awards are located on the NIFA 2009 Award Fact Sheet. NIFA's general award terms and conditions (see link below) is applicable to this program, for awards with an award date on December 26, 2014 and thereafter. https://nifa.usda.gov/resource/nifa-general-terms-and-conditions-grants-and-cooperative-agreements-october-2016.

Information Contacts

Regional or Local Office

None.

Headquarters Office

USDA, NIFA, National Program Leader, Institute of Food Production and Sustainability, Division of Animal Systems, 1400 Independence Avenue, SW., STOP 2240 , Washington , District of Columbia 20250-2240 Email: formulagrantquestions@nifa.usda.gov Phone: (202) 401-4952 Fax: (202) 401-1602

Criteria for Selecting Proposals

2 CFR part 200, Uniform Administrative Requirements, Cost Principles, and Audit Requirements for Federal Awards and 2 CFR part 400 USDA?s Uniform Administrative Requirements, Cost Principles, and Audit Requirements for Federal Awards apply to this program. Within guidelines established for the program as described in the Capacity, Competitive, and/or Non-Competitive Request for Application (RFA). The most current RFAs are available via: https://nifa.usda.gov/program/animal-health-and-disease-research-program.



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