Research on Healthcare Costs, Quality and Outcomes

To support research and evaluations, demonstration projects, research networks, and multidisciplinary centers and to disseminate information on health care and on systems for the delivery of such care involving: (1) The quality, effectiveness, efficiency, appropriateness and value of health care services;

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(2) quality measurement and improvement; (3) the outcomes, cost, cost-effectiveness, and use of health care services and access to such services; (4) clinical practice, including primary care and practice-oriented research; (5) health care technologies, facilities and equipment; (6) health care costs, productivity, organization, and market forces; (7) health promotion and disease prevention, including clinical preventive services; (8) health statistics, surveys, database development, and epidemiology; and (9) patient safety research, including healthcare-associated infections.

In support of this research, the Agency has a special interest in health care and its delivery in the inner city, in rural areas, and for priority populations (low-income groups, minority groups, women, children, the elderly, and individuals with special health care needs).
Related Programs

Examples of Funded Projects

Fiscal Year 2016: AHRQ-supported grants focus on health information technology research, patient safety research, prevention and care management, and quality, effectiveness, and efficiency research.

Fiscal Year 2017: Based on availability of funding, it is anticipated that AHRQ-supported grants will continue to focus on health information technology research, patient safety research, prevention and care management, and quality, effectiveness, and efficiency research.

Fiscal Year 2018: No current data available.

Agency - Department of Health and Human Services

The Department of Health and Human Services is the Federal government's principal agency for protecting the health of all Americans and providing essential human services, especially to those who are least able to help themselves.

Website Address

Relevant Nonprofit Program Categories

Selected Recipients for this Program

RecipientAmount Start DateEnd Date
Regents Of The University Of Michigan $ 386,395   2022-09-012027-06-30
Children's Hospital Of Philadelphia, The $ 144,990   2022-06-032027-05-31
Northshore University Healthsystem $ 136,746   2022-06-012027-05-31
Kaiser Foundation Hospitals $ 400,000   2022-06-012027-03-31
University Of Wisconsin System $ 148,255   2022-04-082027-03-31
Cleveland Clinic Foundation, The $ 148,335   2022-04-012027-03-31
Trustees Of The University Of Pennsylvania, The $ 399,902   2022-05-052027-02-28
Johns Hopkins University, The $ 470,056   2022-05-152027-02-28
University Of Texas Health Science Center Of San Antonio $ 365,980   2022-05-012027-02-28
Children's Hospital Corporation, The $ 398,404   2022-04-012027-02-28

Program Accomplishments

Fiscal Year 2016: AHRQ funded 400 grants. Fiscal Year 2017: AHRQ anticipates funding 329 grants. Fiscal Year 2018: AHRQ anticipates funding 260 grants.

Uses and Use Restrictions

The research should contribute to the health services knowledge base from which empirically based information can be derived by policymakers, both immediately and over the coming decades.

Grants include funds for direct costs (such as personnel, travel, equipment, or supplies) necessary to carry out an approved project as well as funds for the reimbursement of applicable indirect costs (also referred to as facilities and administrative costs).

Unallowable costs are indicated in the HHS Grants Policy Statement.

Eligibility Requirements

Applicant Eligibility

Federal, State or local government agencies, federally-recognized Indian Tribal Governments, U.S.

Territories, non-government organizations,public or private institutions of higher education, and other public or nonprofit private agencies, institutions, or organizations.

For-profit organizations are eligible to apply for these grants only if 'cooperative agreement' is the designated funding mechanism.

Organizations described in section 501(c)4 of the Internal Revenue Code that engage in lobbying are not eligible.

Beneficiary Eligibility

Federal, State or local government agencies, federally-recognized Indian Tribal Governments, public or private nonprofit institutions, U.S. territories, Native American organizations, consumers, students, minority groups, specialized groups, health or education professionals, individuals, scientist/researchers, and the general public.


Nonprofit organizations must submit proof of their nonprofit status when applying for grants. Costs will be determined in accordance with DHHS Regulations 45 CFR 75. 2 CFR 200, Subpart E - Cost Principles applies to this program.

Aplication and Award Process

Preapplication Coordination

Preapplication coordination is not applicable.

Environmental impact information is not required for this program.

This program is excluded from coverage under E.O.


Application Procedures

2 CFR 200, Uniform Administrative Requirements, Cost Principles, and Audit Requirements for Federal Awards applies to this program. Applications must be submitted in response to a Funding Opportunity Announcement (FOA). All FOAs are posted on Refer to the FOA of interest for specific requirements regarding the application procedure. For State agencies, no State Plan is required. Applications are reviewed and evaluated by a group composed primarily of nonfederal scientists. The review is conducted by a panel of experts in the specific study area proposed.

Award Procedures

Applications are reviewed for scientific merit by a committee including nonfederal consultants who are selected from appropriate scientific fields. AHRQ considers the recommendations of the review committee, program interest, and the availability of funds in the final selection of grant applications for funding. When such decisions are made, applicants are notified and a Notice of Award is issued.


Contact the headquarters or regional office, as appropriate, for application deadlines.


Public Health Service Act, Title IX, Public Law 106-129, 42 U.S.C 299 ff; Affordable Care Act, Public Law 111-148.

Range of Approval/Disapproval Time

> 180 Days.


Not Applicable.


If additional support is desired to continue a project beyond the approved project period, an application for competing continuation must be submitted for review in the same manner as a new application.

Assistance Considerations

Formula and Matching Requirements

This program has no statutory formula. This program has no matching requirements. MOE requirements are not applicable to this program.

Length and Time Phasing of Assistance

Grants may be approved for project periods of up to 5 years, depending on the grant program and based on the availability of funding. Refer to the FOA of interest for information regarding the maximum duration of the project period. Awards are made on an annual basis and it is expected that obligations will be made within the budget period awarded. After awards are issued, funds are released in accordance with the payment procedure established by the grantee institution with DHHS, which may be an Electronic Transfer System or a Monthly Cash Request System. Method of awarding/releasing assistance: lump sum.

Post Assistance Requirements


Program reports are not applicable.

Grantees must submit quarterly SF425 reports to PSC.

Progress reports are required on an annual basis.

Some programs also require quarterly progress reports.

A final progress report must be submitted within 90 days after the end of a project period.

Inventions are to be reported immediately.

A Final Invention Statement must be submitted within 90 days after the end of a project period.

An annual Federal Financial Report (FFR; SF425) must be submitted within 90 days after the end of the calendar quarter in which the budget period ends.

A final FFR must be submitted within 90 days after the end of the project period.

Performance monitoring is not applicable.


In accordance with the provisions of 2 CFR 200, Subpart F - Audit Requirements, non-Federal entities that expend financial assistance of $750,000 or more in Federal awards will have a single or a program-specific audit conducted for that year. Non-Federal entities that expend less than $750,000 a year in Federal awards are exempt from Federal audit requirements for that year, except as noted in 2 CFR 200.503. In addition, grants and cooperative agreements are subject to inspection and audits by DHHS and other Federal government officials.


Records must be retained for at least three years; records shall be retained beyond the three year period if audit findings have not been resolved.

Financial Information

Account Identification



(Project Grants) FY 16 $111,070,851; FY 17 est $103,942,348; and FY 18 est $88,635,478

Range and Average of Financial Assistance

$21,908 to $2,674,621; $275,417 average. These are total cost figures (direct costs plus associated facilities and administrative costs, if appropriate).

Regulations, Guidelines, and Literature

42 CFR 67, Regulations for Grants for Health Services Research, Evaluation, Demonstration, and Dissemination Projects as amended by Public Law 106-129; HHS Grants Policy Statement, January 1, 2007.

Information Contacts

Regional or Local Office


Headquarters Office

George Gardner 5600 Fishers Lane, Rockville, Maryland 20857 Phone: 301-427-1447

Criteria for Selecting Proposals

The proposals must first be reviewed by review groups of peers and recommended for approval on the basis of scientific and technical merit. This includes consideration of the qualifications of the principal investigator and staff to conduct the research using appropriate methodology and budget. Those approved proposals which are most relevant to the identified program priority issues of the AHRQ are funded to the extent that funds are available.

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