Epidemiologic Research Studies of Acquired Immunodeficiency Syndrome (AIDS) and Human Immunodeficiency Virus (HIV) Infection in Selected Population Groups

To support research of important HIV-related epidemiologic issues concerning risks of transmission, the natural history and transmission of the disease in certain populations and development and evaluation of behavioral recommendations for reducing AIDS and HIV infection.

Of special interest are
programs that examine these research issues as they affect minority populations (defined as one of the four federally-recognized groups: African-Americans; Asian/Pacific Islanders; Latinos/Hispanics; and Native Americans).

Agency - Department of Health and Human Services

The Department of Health and Human Services is the Federal government's principal agency for protecting the health of all Americans and providing essential human services, especially to those who are least able to help themselves.

Website Address


Selected Recipients for this Program

RecipientAmount Start DateEnd Date
Vietnam National Lung Hospital $ 748,047   2011-09-302018-03-31
University Of North Carolina At Chapel Hill $ 1,773,157   2010-06-152015-06-14
Puerto Rico Department Of Health $ 0   2010-09-302013-09-29
Houston, City Of $ 0   2010-09-302013-09-29
President And Fellows Of Harvard College $ 501,222   2002-09-302009-03-31
Regents Of The University Of California, San Francisco, The $ 9,158,046   2002-09-302008-03-31
Baylor College Of Medicine $ 4,472,051   2002-09-302008-03-31
Administrators Of The Tulane Educational Fund, The $ 37,615,355   2002-09-302008-03-31
Johns Hopkins University $ 40,685,040   2002-09-302008-03-31
University Of Medicine And Dentistry Of Nj (inc) $ 3,838,000   2002-09-302008-03-31

Program Accomplishments

Not Applicable.

Uses and Use Restrictions

Assistance is provided to support cooperative agreements that examine important epidemiologic research issues concerning AIDS and HIV infection.

The research should contribute to the health services knowledge base from which empirically based information can be derived by policy makers, both immediately and over the coming decades.

Grants include funds for direct costs (such as personnel, travel, equipment, or supplies) necessary to carry out an approved project as well as funds for the reimbursement of applicable indirect costs.

Unallowable costs, as well as those for which prior written approval is required, are indicated in the PHS Grants Policy Statement.

Eligibility Requirements

Applicant Eligibility

Eligible applicants include States, political subdivisions of States or their agents or instrumentalities, private research organizations, including American Indian/Alaska Native tribal governments or tribal organizations located wholly or in part within their boundaries, other public and private nonprofit organizations, and for-profit organizations.

Beneficiary Eligibility

State and local health agencies; private research organizations, public and private nonprofit organizations, for profit organizations; minority groups; including American Indian/Alaska Native tribal governments or tribal organizations located wholly or in part within their boundaries, and persons physically afflicted with AIDS/HIV infection.


Costs will be determined by HHS Regulations 45 CFR Part 74, for nonprofit organizations and in accordance with OMB Circular No. A-87, 'Cost Principles for State and Local Governments;'. 2 CFR 200, Subpart E - Cost Principles applies to this program.

Aplication and Award Process

Preapplication Coordination

Preapplication coordination is not applicable.

Environmental impact information is not required for this program.

This program is excluded from coverage under E.O.


Application Procedures

2 CFR 200, Uniform Administrative Requirements, Cost Principles, and Audit Requirements for Federal Awards applies to this program. Applicants must download application forms from www.Grants.gov. Applications must be submitted electronically at www.Grants.gov. If an applicant does not have access to the Internet, or if they have difficulty accessing the forms on-line, contact the CDC Office Grants Services Technical Information Management Section (OGSTIMS) staff. For this, or further assistance, contact OGSTIMS: Telephone (770) 488-2700, Email: OGSTIMS@cdc.gov.

Award Procedures

After review and approval, a notice of award (NoA) is prepared and processed, along with appropriate notification to the public, initial award provides funds for first budget period (usually 12 months) and Notice of Award indicates support recommended for the remainder of project period, allocation of Federal funds by budget categories, and special conditions, if any. However, applicants are encouraged to call CDC for programmatic technical assistance prior to the development and submission of their assistance application.


Contact the headquarters or regional office, as appropriate, for application deadlines.


Public Health Act, Section 301.

Range of Approval/Disapproval Time

From 120 to 180 days. About 3 - 6 months from receipt of application.


As stated in the Terms and Conditions.


If additional support is desired to continue a research project beyond the approved project period, an application for competing continuation must be submitted for review in the same manner as a new application.

Assistance Considerations

Formula and Matching Requirements

This program has no statutory formula. Matching requirements are not applicable to this program. MOE requirements are not applicable to this program.

Length and Time Phasing of Assistance

Assistance is available for a 12-month budget period within project periods ranging from one to four years. After awards are issued, funds are released in accordance with the payment procedure established by the grantee institution with DHHS, which may be an Electronic Transfer System or a Monthly Cost Request System. Method of awarding/releasing assistance: by letter of credit.

Post Assistance Requirements


See FOA for details.

Cash reports are not applicable.

Progress reports are not applicable.

Expenditure reports are not applicable.

See notice of funding opportunity (NOFO) for details.


In accordance with the provisions of 2 CFR 200, Subpart F - Audit Requirements, non-Federal entities that expend financial assistance of $750,000 or more in Federal awards will have a single or a program-specific audit conducted for that year. Non-Federal entities that expend less than $750,000 a year in Federal awards are exempt from Federal audit requirements for that year, except as noted in 2 CFR 200.503. In addition, grants and cooperative agreements are subject to inspection and audits by DHHS and other Federal government officials.


Financial records, supporting documents, statistical records, and all other records pertinent to the project must be kept readily available for review by personnel authorized to examine PHS grant accounts. Records must be maintained for a minimum of 3 years after the end of a budget period. If questions still remain, such as those cited as a result of an audit, records must be retained until completion or resolution of any audit in process or pending resolution. Property records must be retained in accordance with PHS Grants Policy Statement requirements.

Financial Information

Account Identification



(Cooperative Agreements) FY 16 $2,500,000; FY 17 est $1,950,000; and FY 18 est $600,000

Range and Average of Financial Assistance

No Data Available.

Regulations, Guidelines, and Literature

Regulations governing this program are published in the application kit. PHS Grants Policy Statement No. 94-50,000 (Revised) April l, 1994.

Information Contacts

Regional or Local Office


Headquarters Office

Elizabeth Wolfe 1600 Clifton Road, NE, Mailstop E-07, Atlanta, Georgia 30333 Email: eow1@cdc.gov Phone: (404) 639-8531

Criteria for Selecting Proposals

Applications will be reviewed and evaluated based on the evidence submitted which specifically describes the applicant's abilities to meet the following criteria: (1) the plans to develop and implement the study describing how study participants will be identified, enrolled, tested and followed; (2) the ability to enroll and follow an adequate number of eligible study participants to assure proper conduct of the study. This includes both demonstration of the availability of HIV-infected potential study participants and the experience of the investigator in enrolling and following such persons; (3) the applicant's current activities in AIDS and HIV research and how they will be applied to achieving the objectives of the study; letters of support from cooperating organizations that demonstrate that nature and extent of such cooperation should be included; (4) the applicant's understanding of the research study objectives and, their ability, willingness and/or need to collaborate with CDC and researchers from other study sites in study design and analysis, including use of common forms, and sharing of specimens and data; (5) the plan to protect the rights and confidentiality of all participants and ensure adequate participation; (6) the size, qualifications and time allocation of the proposed staff and the availability of facilities to be used during the research study; (7) how the project will be administered to assure the proper management of the daily activities of the program; (8) the proposed schedule for accomplishing the activities of the research; including time frames; and (9) the quality of an evaluation plan which specifies methods and instruments to be used to evaluate the progress made in attaining research objectives.

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