Fertility Status as a Marker for Overall Health (R21 Clinical Trial Optional)

The purpose of this funding opportunity announcement (FOA) is to support exploratory/developmental research that explores the premise that fertility status can be a marker for overall health.

It is clear that chronic conditions such as cancer, diabetes, and obesity can impair fertility, however

less is known about the extent to which fertility status can impact or act as a marker for overall health.

Data suggest that infertility is not necessarily a unique disease of the reproductive axis, but is often physiologically or genetically linked with other diseases and conditions.

Recent epidemiologic studies demonstrate links between fertility status in both males and females and various somatic diseases and disorders.

Taken together, these data strongly suggest that fertility status can be a window into overall health.

This FOA focuses on studies evaluating fertility as a marker for overall health and therefore applications that look at the effects of a disease or disorder on fertility are outside the scope of this program.


Office: National Institutes of Health

Estimated Funding: $300,000

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Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U. S. Territory or Possession.

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