Microbial-based Cancer Imaging and Therapy - Bugs as Drugs (R01 Clinical Trial Not Allowed)

This Funding Opportunity Announcement (FOA) solicits grant applications proposing to utilize bacteria, archaebacteria, bacteriophages, or other non-oncolytic viruses and their natural products to study the underlying mechanisms of the complex interactions between microorganisms, tumors, and the immune

credit:


system, and to explore their clinical potential for cancer imaging, therapeutics or diagnostics.

Projects can focus on using microorganisms as anti-tumor agents, as activators of anti-tumor immunity, or as delivery vehicles for treatment, diagnosis, or imaging, complementing or synergizing with existing tools and approaches.

This FOA will support basic mechanistic and preclinical studies in cell culture and animal models.

Applicants are encouraged to address both the microbial and tumor aspects of microbial tumor interactions relevant to microbial-based cancer therapy (including therapies for oral cancer), tumor imaging, tumor detection, or diagnosis.

This funding opportunity is part of broader NCI-sponsored research on microbial-based cancer therapy.

(link to OCCAM)
Related Programs

Oral Diseases and Disorders Research

Department of Health and Human Services


Cancer Treatment Research

Department of Health and Human Services


Cancer Biology Research

Department of Health and Human Services


Agency: Department of Health and Human Services

Office: National Institutes of Health

Estimated Funding: $4,828,305


Who's Eligible



Obtain Full Opportunity Text:
http://grants.nih.gov/grants/guide/pa-files/PAR-22-085.html

Additional Information of Eligibility:
Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U. S. Territory or Possession.

Full Opportunity Web Address:
http://grants.nih.gov/grants/guide/pa-files/PAR-22-085.html

Contact:


Agency Email Description:
See Section VII. Agency Contacts within the full opportunity announcement for all other inquires.

Agency Email:


Date Posted:
2022-02-18

Application Due Date:


Archive Date:
2025-06-12


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