Natural History Studies Addressing Unmet Needs of Rare Diseases: Orphan Products Research Project Grant (R01)

The purpose of this funding opportunity announcement (FOA) is to support studies that advance medical product development through the characterization of the natural history of rare diseases/conditions with unmet needs.

Through the support of efficient and innovative natural history studies, FDA


expects to address critical knowledge gaps, to remove major barrier(s) to progress in the field, to exert a significant and broad impact on a specific rare disease or multiple rare diseases with similar pathophysiology, and to inform current or future product development including the design of clinical trial(s) and to ultimately inform the development of medical products that meet patient needs.

Related Programs

Food and Drug Administration Research

Department of Health and Human Services

Agency: Department of Health and Human Services

Office: Food and Drug Administration

Estimated Funding: $1,100,000

Relevant Nonprofit Program Categories

Obtain Full Opportunity Text:
Full application announcement

Additional Information of Eligibility:
The JFSP encourages proposals from all interested parties.

However, because the focus of the JFSP is on wildland fire and fuels issues on federal wildlands, evidence of direct involvement by federal scientists or land managers in the development of proposals must be included in all proposals.

Funding awards will be made by the Bureau of Land Management only to the federal agency sponsoring the selected project(s).

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